Should I make wudu before going to sleep?

Yes, it is recommended. The Prophet ﷺ taught Muslims to go to bed in a state of wudu. It is a sunnah, not an obligation, and it only takes a minute. It lets you end the day in worship, and if you skip it on a tired night, you have not sinned.
What the Prophet ﷺ taught
Al-Bara' ibn Azib reported that the Prophet ﷺ said to him: "Whenever you go to bed, perform ablution like that for the prayer, lie on your right side and say [the bedtime supplication]. Then if you die on that very night, you will die with faith." He added that these words should be the last thing you say before sleep (Sahih al-Bukhari 247).
So the bedtime sunnah has three parts: wudu, lying on your right side, and a closing dua. See What should I say before sleeping?
Is it required?
No. Scholars understand the Prophet's ﷺ instruction as a recommendation (mustahabb). It is a habit that earns extra reward, but nobody has to repeat their wudu just because it is bedtime. If you made wudu for Isha and nothing has broken it since, you are already going to bed in wudu.
The case of a person in janabah (who needs a full bath) is a little different. The Prophet ﷺ used to wash his private parts and make wudu like the prayer before sleeping in that state (Sahih al-Bukhari 288). See Can I sleep in a state of janabah?
Will my wudu last all night?
Not necessarily. Most scholars say deep sleep breaks wudu, so if you wake up for tahajjud or Fajr, you make wudu again. That does not make the bedtime wudu pointless. The sunnah is about the state you go to sleep in and the intention to wake up and worship. See Does sleeping break wudu?
A simple bedtime routine
- Make wudu as you normally do: say Bismillah, wash your hands, rinse your mouth and nose, wash your face and arms, wipe your head and ears, and wash your feet.
- Switch off the lights and lie on your right side.
- Say your bedtime dua, and try to make it the last thing you say.
- If you are using a phone alarm for Fajr, set it before wudu so nothing distracts you afterwards.
If you are new to wudu, the steps are simple. See How do I make wudu?
- Sleeping in wudu is a recommended sunnah (Sahih al-Bukhari 247).
- It is not obligatory, and missing it is not a sin.
- If your wudu from the night prayer is still intact, you already have it.
- Deep sleep breaks wudu, so renew it if you wake up to pray.
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